She was born in Mantua in 1965 and has been Chairman of Eni since May 2014. She has been Chairman of the Fondazione Eni Enrico Mattei since November 2014. She is also Chairman and CEO of Marcegaglia Holding SpA and Deputy Chairman and CEO of the subsidiary companies operating in the processing of steel. She is also Chairman and CEO of Marcegaglia Investments Srl, the holding company of the diversified activities of the group. She is a member of the Board of Directors of Bracco SpA and Gabetti Property Solutions SpA.
From 1994 to 1996 she was National Deputy President of Young Entrepreneurs of Confindustria, from 1997 to 2000 she was President of the European Confederation of the Young Entrepreneurs (YES), from 1996 to 2000 President of Young Italian Entrepreneurs of Confindustria and from 2000 to 2002 she was Vice President of Confindustria for Europe.
From May 2004 to May 2008 she was Confindustria Vice President for infrastructures, energy, transport and environment and Italian Representative of the top High Level Group for energy, competitiveness and environment set up by the European Commission. From May 2008 to May 2012 she was President of Confindustria. From July 2013 to July 2018 she was President of Businesseurope. She was a member of the Management Board of Banco Popolare and Director of Finecobank SpA and Italcementi SpA. She held the position of Chairman of the Aretè Onlus Foundation. From July 2010 to June 2019 she was President of the University Luiss Guido Carli.
She graduated in Business Administration at the Bocconi University in Milan and attended a Master in Business Administration at New York University.